Headlands Research is a multinational network of clinical trial sites focused on large-volume recruitment and retention of diverse, inclusive patient populations, delivering the highest-quality data to sponsors and CROs.
Headlands Research Northern California sites bring over 25 years of clinical research experience, established community relationships, and a commitment to advancing healthcare through clinical trials. Formerly known as Clinical Trials Research, these sites have proudly served participants and research partners for more than two decades, conducting high-quality clinical studies while providing compassionate care and personalized support to every participant.
Led by Site President and Principal Investigator Jeffrey D. Wayne, MD, our sites continue to provide experienced clinical leadership and individualized attention throughout every study. Dr. Wayne has served as a Principal Investigator since 1992, overseeing more than 300 clinical trials. Since 2010, he has dedicated his practice exclusively to clinical research and remains actively involved in study oversight, participant care, and the advancement of innovative treatment options.
Clinical research depends on the commitment of volunteers who choose to participate in advancing medical knowledge and helping bring new therapies to future generations. Our experienced team is dedicated to creating a safe, supportive, and respectful environment where participants feel informed and valued throughout their clinical trial journey.
As part of Headlands Research, our Northern California sites combine their deep local expertise with the resources, infrastructure, and operational excellence of a leading research network. This partnership enhances our ability to provide high-quality clinical trial opportunities for participants while delivering reliable study execution for sponsors and research partners.
Whether you are considering participating in a clinical trial or seeking an experienced research partner, Headlands Research is committed to advancing medicine through collaboration, innovation, and a shared dedication to improving lives.
Principal Investigator Site President
Jeffrey D. Wayne, MD, is a board-certified internist, founder of Clinical Trials Research, and Site President of Headlands’ Northern California research sites. Dr. Wayne earned his medical degree from the Keck School of Medicine at the University of Southern California and has dedicated more than three decades to patient care and advancing clinical research.
With more than 30 years of experience as a Principal Investigator, Dr. Wayne has led approximately 300 Phase 2, Phase 3, and Phase 4 clinical trials across a broad range of therapeutic areas, including Alzheimer’s disease, hypertension, diabetes, cardiovascular disease, respiratory conditions, women’s health, and men’s health. Since 2010, he has focused exclusively on clinical research, providing experienced medical oversight and advancing the development of innovative therapies.
As the founder of Clinical Trials Research, now proudly part of the Headlands Research Network, Dr. Wayne has built a research organization grounded in physician leadership, operational excellence, and an unwavering commitment to participant safety and experience. He remains actively involved in every aspect of clinical trial oversight, ensuring scientific integrity while providing participants with personalized, compassionate care throughout their research journey.
In addition to his clinical research leadership, Dr. Wayne served as Volunteer Clinical Faculty with the University of California, Davis School of Medicine, contributing to the education and mentorship of future physicians and healthcare professionals.
Through his dedication to medicine and clinical research, Dr. Wayne continues to help bring innovative treatments forward while advancing medical knowledge and improving healthcare outcomes for communities throughout Northern California and beyond.
Sub-Investigator (Sacramento)
Esther Gayoba is a certified Physician Assistant who brings an extensive background in emergency medicine, occupational health, and women's health to the Sacramento research team. She earned her Physician Assistant Certificate from Long Island University/The Brooklyn Hospital Center and later obtained a Master of Science in Healthcare Management from California State University, Los Angeles. Throughout her diverse career, Esther has managed complex clinical cases across premier health systems, including Sutter Occupational Health and the USC Los Angeles County Medical Center. Since joining Clinical Trials Research in May 2023, she has served as a Sub-Investigator across an array of complex Phase 2 and Phase 3 trials, including specialized protocols for metabolic liver diseases, cardiovascular health, and postmenopausal care.
A board-certified psychiatrist, Dr. Herts has been involved in clinical trials of investigational treatments for CNS disorders including MDD, treatmentresistant depression, OCD, bipolar disorder, ADD/ADHD, and migraines.
Dr. Herts is a clinical research investigator at Pharmasite Research. Additionally, she is a clinical psychiatrist in private practice in Baltimore, MD and a psychiatrist at Sheppard and Enoch Pratt Hospital. As a research investigator, Dr. Herts has worked on numerous clinical trials of investigational treatments for central nervous system disorders, including major depression, treatment-resistant depression, bipolar disorder, ADD/ADHD, obsessive-compulsive disorder (OCD), and migraine headache.
Dr. Herts earned her medical degree from the West Virginia School of Osteopathic Medicine and completed her residency in Psychiatry at the University of Maryland and Sheppard and Enoch Pratt Hospital. She is board certified by the American Board of Psychiatry. She specializes in the treatment and research of depression, anxiety, bipolar disorder, addiction, PTSD, OCD, ADHD, and personality disorders in the adult population. Dr. Herts provides a collaborative, comprehensive, and holistic approach and values continuity of care with other providers and her patients’ loved ones when appropriate and permitted.
A board-certified psychiatrist, Dr. Dubin has been involved in clinical trials of investigational treatments for MDD, treatment-resistant depression, OCD, PTSD, and more.
Dr. Dubin is a clinical research investigator at Pharmasite Research and a solo practitioner in her private practice in Baltimore, MD. She is also a Coordinator of Psychiatric Education and Training for the Behavioral Health Administration of the state of Maryland and an Associate Training Director in the University of Maryland/Sheppard Pratt Psychiatry Residency Training Program. Board certified in psychiatry and neurology, Dr. Dubin’s clinical interests include mood and anxiety disorders, and her research experience covers obsessive-compulsive disorder (OCD), major depressive disorder (MDD), treatment-resistant depression, and PTSD.
Dr. Dubin earned her medical degree and completed her residency at the University of Maryland School of Medicine, and she completed an extramural fellowship in cognitive therapy at the Beck Institute for Cognitive Therapy. She has held academic teaching positions in psychiatry at the University of Maryland School of Medicine and Johns Hopkins Medicine. Dr. Dubin is also a member of the Maryland Psychiatric Society, Distinguished Fellow of the American Psychiatric Association, and Founding Fellow of the Academy of Cognitive Therapy.
Dr. Dubin contributes her time to her community as well as other medical professionals. During her time as Associate Training Director of the Adult Outpatient Psychiatry Clinic, she developed an acute crisis intervention program to provide urgent services to medical students in crisis as well as the “Residents’ PA Clinic” that continues to allow residents to see additional patient populations they would not normally encounter in their clinical site. During the COVID-19 pandemic, she volunteered for the Physician Support Line, a national program to support physicians. She has also served on the boards of several local non-profit organizations that support a range of causes, from women experiencing infertility to violence prevention. She is proficient in Hebrew and has a working knowledge of Spanish.
Dr. Hnoosh’s experience spans primary care practice, clinical research, and entrepreneurship, and she delivers the highest quality care to her patients in all settings.
Dr. Hnoosh is Principal Investigator at Pharmasite Research, a primary care physician in the Ambulatory and Emergency Care Clinical Center (AECCC) and women’s health clinic at the Baltimore VA Medical Center, and a primary care physician offering telemedicine services for AkosMD. She is also CEO, owner, and founder of Celesticare, LL, a special needs and elderly care medical equipment retailer that supplies directly to customers as well as to businesses. Dr. Hnoosh’s research experience includes Alzheimer’s disease and other dementias, migraine, diabetes, endometrial cancer, and pancreatic cancer.
Dr. Hnoosh earned her medical degrees at the University of Baghdad School of Medicine in Iraq and Xavier University School of Medicine in Aruba. She completed her residency in internal medicine at Medstar Health Internal Medicine and a fellowship in geriatric medicine at the University of Maryland Medical Center, both in Baltimore, MD. She is currently an Adjunct Assistant Professor in the Department of Medicine at the University of Maryland School of Medicine and mentors fellows in geriatric medicine and nurse practitioners at Baltimore VA Hospital.
Bio Coming Soon!
Alan Jonas, M.D is a clinical research investigator and co-owner of Pharmasite Research, Inc., a clinical trials company dedicated to industry sponsored neuroscience outpatient research. Pharmasite Research, Inc. has been in existence for 11 years and is widely respected for quality clinical research. Dr Jonas has functioned as the principal investigator or sub investigator in over 80 clinical trials in areas including depression, bipolar disorders, anxiety disorders, ADD in adults and children, geriatric depression, dementia of the Alzheimer’s type and vascular type, sleep disorders, fibromyalgia, sexual dysfunction associated with antidepressant treatment, and schizophrenia. He is the author or co author of several research papers resulting from these studies.
In addition Dr. Jonas is a board certified adult and geriatric psychiatrist and has been active in a mental health oriented group private practice for the past 21 years. His areas of expertise include neuropsychiatry, psychopharmacology, geriatric psychiatry, mood disorders and adult ADD.
Dr. Jonas serves on the faculty or speakers bureau of seven pharmaceutical companies, including the national speakers bureau of Wyeth Pharmaceuticals.
He has given over 300 lectures and presentations and is invited and actively travels throughout the United States presenting psychopharmacologic industry sponsored lectures and case presentations and non industry CME lectures as well as participating in advisory boards.
Robert B. Lehman, M.D is practice director of Psychiatric Consultants, an outpatient psychiatric practice in Baltimore Maryland. He is also a partner and clinical research investigator at Pharmasite Research, and a psychiatrist at Sinai Hospital of Baltimore. As a principal investigator, he has examined the efficacy and safety profiles of various treatment options for a broad range of mental illnesses, including generalized anxiety disorder, panic disorder, social anxiety disorder, major depressive disorder, treatment resistant depression, obsessive-compulsive disorder, and schizophrenia, bipolar disorder, ADD/ADHD, child and adolescent depression and bipolar disorder, primary insomnia, co-morbid insomnia, Alzheimer’s Disease, and cognition studies.
Dr. Lehman is board certified by the American Board of Psychiatry and Neurology and is an active member of the America Psychiatric Association, the Medical and Chirurgical Society of Maryland, the Baltimore County Medical Association, and the Maryland Psychiatric Society. He is a Fellow of the American Psychiatric Association. He is past also Chairman of Education the P’TACH School in Baltimore, Maryland.
Dr. Lehman has served as a consultant in the Traumatic Brain Injury Unit at Sinai Hospital of Baltimore. He is also a clinical instructor in the department of psychiatry at the University of Maryland School of Medicine.
During his career, Dr. Lehman has authored and co-authored several scientific reports that have appeared in many leading journals, including Psychiatric Times, The Journal of Psychiatry and Neuroscience, CNS Spectrums, and Primary Psychiatry and Pediatrics. He has presented posters at Institute for Psychiatric Services Annual Meeting, NCDEU, and the US Psychiatric Congress.
Dr. Lehman earned his medical degree from the University of Maryland School of Medicine. He also completed his residency in Psychiatry and a fellowship in Child Psychiatry at Sheppard and Enoch Pratt Hospital in Towson, Maryland.
"*" indicates required fields